Aleksunes, L. M.: search on Z-Library

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1

Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation

Klaassen, C. D., Aleksunes, L. M.

Journal:

Pharmacological Reviews

Year:

2010

Language:

english

File:

PDF, 6.82 MB

english, 2010

2

Interindividual regulation of the BCRP/ABCG2 transporter in term human placentas

Bircsak, Kristin M, Moscovitz, Jamie E, Wen, Xia, Archer, Faith, Yuen, Poi Yu Sofia, Mohammed, Moiz, Memon, Naureen, Weinberger, Barry I, Saba, Laura M, Vetrano, Anna M, Aleksunes, Lauren M

Journal:

Drug Metabolism and Disposition

Year:

2018

Language:

english

File:

PDF, 491 KB

english, 2018

3

Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase

Szilagyi, John T., Fussell, Karma C., Wang, Yun, Jan, Yi-Hua, Mishin, Vladimir, Richardson, Jason R., Heck, Diane E., Yang, Shaojun, Aleksunes, Lauren M., Laskin, Debra L., Laskin, Jeffrey D.

Journal:

Toxicology and Applied Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.64 MB

english, 2018

4

Pharmacokinetic determinants of cisplatin-induced subclinical kidney injury in oncology patients

Ibrahim, Mustafa E., Chang, Cara, Hu, Yichun, Hogan, Susan L., Mercke, Nickie, Gomez, Madeleine, O’Bryant, Cindy L., Bowles, Daniel W., George, Blessy, Wen, Xia, Buckley, Brian, Aleksunes, Lauren, Joy

Journal:

European Journal of Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 517 KB

english, 2018

5

Restoration of enterohepatic bile acid pathways in pregnant mice following short term activation of Fxr by GW4064

Moscovitz, Jamie E., Kong, Bo, Buckley, Kyle, Buckley, Brian, Guo, Grace L., Aleksunes, Lauren M.

Journal:

Toxicology and Applied Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.20 MB

english, 2016

6

Management of Rosiglitazone-Induced Edema: Two Case Reports and a Review of the Literature

Wang, Fei, Aleksunes, Lauren M., Reagan, Louise A., Vergara, Cunegundo M.

Journal:

Diabetes Technology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 142 KB

english, 2002

7

Renal and Hepatic Transporter Expression in Type 2 Diabetic Rats

Manautou, Jose, Nowicki, Michael, Aleksunes, Lauren, Sawant, Sharmilee, Dnyanmote, Ankur, Mehendale, Harihara

Journal:

Drug Metabolism Letters

Year:

2008

Language:

english

File:

PDF, 661 KB

english, 2008

8

Transcription factor-mediated regulation of the BCRP/ ABCG2 efflux transporter: a review across tissues and species

Gorczyca, Ludwik, Aleksunes, Lauren M.

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2020

Language:

english

File:

PDF, 1.22 MB

english, 2020

9

Advancing computer-aided drug discovery (CADD) by big data and data-driven machine learning modeling

Zhao, Linlin, Ciallella, Heather L., Aleksunes, Lauren M., Zhu, Hao

Journal:

Drug Discovery Today

Year:

2020

File:

PDF, 2.34 MB

2020

10

Gender divergent expression of Nqo1 in Sprague Dawley and August Copenhagen x Irish rats

Lisa M. Augustine, Craig D. Fisher, Andrew J Lickteig, Lauren M. Aleksunes, Angela L. Slitt, Nathan J. Cherrington

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2008

Language:

english

File:

PDF, 249 KB

english, 2008

11

Transgenic Expression of the Human MRP2 Transporter Reduces Cisplatin Accumulation and Nephrotoxicity in Mrp2-Null Mice

Wen, Xia, Buckley, Brian, McCandlish, Elizabeth, Goedken, Michael J., Syed, Samira, Pelis, Ryan, Manautou, José E., Aleksunes, Lauren M.

Journal:

The American Journal of Pathology

Year:

2014

Language:

english

File:

PDF, 2.17 MB

english, 2014

12

Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in mice

Rudraiah, Swetha, Moscovitz, Jamie E., Donepudi, Ajay C., Campion, Sarah N., Slitt, Angela L., Aleksunes, Lauren M., Manautou, José E.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.90 MB

english, 2014

13

Efflux Transporter Expression and Acetaminophen Metabolite Excretion Are Altered in Rodent Models of Nonalcoholic Fatty Liver Disease

Lickteig, A. J., Fisher, C. D., Augustine, L. M., Aleksunes, L. M., Besselsen, D. G., Slitt, A. L., Manautou, J. E., Cherrington, N. J.

Journal:

Drug Metabolism and Disposition

Year:

2007

Language:

english

File:

PDF, 462 KB

english, 2007

14

Compensatory Induction of Liver Efflux Transporters in Response to ANIT-Induced Liver Injury Is Impaired in FXR-Null Mice

Cui, Y. J., Aleksunes, L. M., Tanaka, Y., Goedken, M. J., Klaassen, C. D.

Journal:

Toxicological Sciences

Year:

2009

Language:

english

File:

PDF, 1.36 MB

english, 2009

15

Identification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its Metabolites

Scialis, Renato J., Aleksunes, Lauren M., Csanaky, Iván L., Klaassen, Curtis D., Manautou, José E.

Journal:

Drug Metabolism and Disposition

Year:

2019

File:

PDF, 928 KB

2019

16

Renal efflux transporter expression in pregnant mice with Type I diabetes

Lindsay L. Yacovino, Lauren M. Aleksunes

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

17

Inflammatory Regulation of ATP Binding Cassette Efflux Transporter Expression and Function in Microglia

Gibson, C. J., Hossain, M. M., Richardson, J. R., Aleksunes, L. M.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 3.99 MB

english, 2012

18

Pregnancy Represses Induction of Efflux Transporters in Livers of Type I Diabetic Mice

Lauren M. Aleksunes, Jialin Xu, Eugenia Lin, Xia Wen…

Journal:

Pharmaceutical Research

Year:

2013

Language:

english

File:

PDF, 725 KB

english, 2013

19

Differential Expression of Mouse Hepatic Transporter Genes in Response to Acetaminophen and Carbon Tetrachloride

Aleksunes, L. M.

Journal:

Toxicological Sciences

Year:

2004

Language:

english

File:

PDF, 278 KB

english, 2004

20

Altered Disposition of Acetaminophen in Nrf2-null and Keap1-knockdown Mice

Reisman, S. A., Csanaky, I. L., Aleksunes, L. M., Klaassen, C. D.

Journal:

Toxicological Sciences

Year:

2009

Language:

english

File:

PDF, 726 KB

english, 2009

21

Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function

Campion, S. N., Johnson, R., Aleksunes, L. M., Goedken, M. J., van Rooijen, N., Scheffer, G. L., Cherrington, N. J., Manautou, J. E.

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2008

Language:

english

File:

PDF, 1.99 MB

english, 2008

22

Nrf2- and PPAR -Mediated Regulation of Hepatic Mrp Transporters after Exposure to Perfluorooctanoic Acid and Perfluorodecanoic Acid

Maher, J. M., Aleksunes, L. M., Dieter, M. Z., Tanaka, Y., Peters, J. M., Manautou, J. E., Klaassen, C. D.

Journal:

Toxicological Sciences

Year:

2008

Language:

english

File:

PDF, 573 KB

english, 2008

23

Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium

Oshida, Keiyu, Vasani, Naresh, Thomas, Russell S., Applegate, Dawn, Rosen, Mitch, Abbott, Barbara, Lau, Christopher, Guo, Grace, Aleksunes, Lauren M., Klaassen, Curtis, Corton, J. Christopher, Guillou

Journal:

Year:

2015

Language:

english

File:

PDF, 4.28 MB

english, 2015

24

Brain region‐specific regulation of histone acetylation and efflux transporters in mice

You, Dahea, Shin, Hye Min, Mosaad, Fatimah, Richardson, Jason R., Aleksunes, Lauren M.

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2019

Language:

english

File:

PDF, 617 KB

english, 2019

25

Trophoblast Syncytialization and Efflux of Cyclic Nucleotides by MRP Transporters

Gorczyca, Ludwik, Aleksunes, Lauren

Journal:

Year:

2019

Language:

english

File:

PDF, 71 KB

english, 2019

26

Analysis of changes in hepatic gene expression in a murine model of tolerance to acetaminophen hepatotoxicity (autoprotection)

O'Connor, Meeghan A., Koza-Taylor, Petra, Campion, Sarah N., Aleksunes, Lauren M., Gu, Xinsheng, Enayetallah, Ahmed E., Lawton, Michael P., Manautou, José E.

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.80 MB

english, 2014

27

Introducing the "TCDD-Inducible AhR-Nrf2 Gene Battery"

Yeager, R. L., Reisman, S. A., Aleksunes, L. M., Klaassen, C. D.

Journal:

Toxicological Sciences

Year:

2009

Language:

english

File:

PDF, 628 KB

english, 2009

28

Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver

Zhu, Yan, Li, Guodong, Dong, Yafeng, Zhou, Helen H., Kong, Bo, Aleksunes, Lauren M., Richardson, Jason R., Li, Fei, Guo, Grace L.

Journal:

Toxicology and Applied Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.01 MB

english, 2013

29

Coordinated Expression of Multidrug Resistance-Associated Proteins (Mrps) in Mouse Liver during Toxicant-Induced Injury

Aleksunes, L. M.

Journal:

Toxicological Sciences

Year:

2006

Language:

english

File:

PDF, 1.56 MB

english, 2006

30

Renal and Hepatic Transporter Expression in Type 2 Diabetic Rats

Manautou, Jose, Nowicki, Michael, Aleksunes, Lauren, Sawant, Sharmilee, Dnyanmote, Ankur, Mehendale, Harihara

Journal:

Drug Metabolism Letters

Year:

2008

File:

PDF, 661 KB

2008

31

Correlation between Conjugated Bisphenol A Concentrations and Efflux Transporter Expression in Human Fetal Livers

Moscovitz, J. E., Nahar, M. S., Shalat, S. L., Slitt, A. L., Dolinoy, D. C., Aleksunes, L. M.

Journal:

Drug Metabolism and Disposition

Year:

2016

Language:

english

File:

PDF, 324 KB

english, 2016

32

241: Modulation of hormone secretion by the environmental chemical zearalenone in trophoblasts differentiated from human embryonic stem cells

Gupta, Vivek, Bircsak, Kristin, Lu, Chi-Wei, Aleksunes, Lauren

Journal:

American Journal of Obstetrics and Gynecology

Year:

2015

Language:

english

File:

PDF, 51 KB

english, 2015

33

Activation of NRF2 Signaling in HEK293 Cells by a First-in-Class Direct KEAP1-NRF2 Inhibitor

Wen, Xia, Thorne, Gabriell, Hu, Longqin, Joy, Melanie S., Aleksunes, Lauren M.

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2015

Language:

english

File:

PDF, 559 KB

english, 2015

34

NF-E2-Related Factor 2 Inhibits Lipid Accumulation and Oxidative Stress in Mice Fed a High-Fat Diet

Tanaka, Y., Aleksunes, L. M., Yeager, R. L., Gyamfi, M. A., Esterly, N., Guo, G. L., Klaassen, C. D.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2008

Language:

english

File:

PDF, 399 KB

english, 2008

35

Fetal Exosomal Platelet-activating Factor Triggers Functional Progesterone Withdrawal in Human Placenta

Palomares, Kristy T., Parobchak, Nataliya, Ithier, Mayra Cruz, Aleksunes, Lauren M., CastaÃ±o, Paula M., So, Melody, Faro, Revital, Heller, Debra, Wang, Bingbing, Rosen, Todd

Journal:

Reproductive Sciences

Year:

2020

File:

PDF, 4.09 MB

2020

36

Induction of Hepatobiliary Efflux Transporters in Acetaminophen-Induced Acute Liver Failure Cases

Barnes, S. N., Aleksunes, L. M., Augustine, L., Scheffer, G. L., Goedken, M. J., Jakowski, A. B., Pruimboom-Brees, I. M., Cherrington, N. J., Manautou, J. E.

Journal:

Drug Metabolism and Disposition

Year:

2007

Language:

english

File:

PDF, 418 KB

english, 2007

37

Prominent Expression of Xenobiotic Efflux Transporters in Mouse Extraembryonic Fetal Membranes Compared with Placenta

Aleksunes, L. M., Cui, Y., Klaassen, C. D.

Journal:

Drug Metabolism and Disposition

Year:

2008

Language:

english

File:

PDF, 689 KB

english, 2008

38

Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases: a meeting report of the 21 st International Symposium on Microsomes and Drug Oxidations (MDO)

Yu, Ai-Ming, Ingelman-Sundberg, Magnus, Cherrington, Nathan J., Aleksunes, Lauren M., Zanger, Ulrich M., Xie, Wen, Jeong, Hyunyoung, Morgan, Edward M., Turnbaugh, Peter J., Klaassen, Curtis D., Bhatt,

Journal:

Acta Pharmaceutica Sinica B

Year:

2017

Language:

english

File:

PDF, 310 KB

english, 2017

39

Differential Regulation of Transporters in Human Placental Cells and Primary Explants in Response to Hypoxia

Aleksunes, Lauren, Gorczyca, Ludwik, Du, Jianyao, Bircsak, Kristin, Wen, Xia, Vetrano, Anna

Journal:

Year:

2019

Language:

english

File:

PDF, 70 KB

english, 2019

40

Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes

Scott A. Reisman, Lauren M. Aleksunes, Curtis D. Klaassen

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 746 KB

english, 2009

41

Nuclear Factor Erythroid 2-Related Factor 2 Deletion Impairs Glucose Tolerance and Exacerbates Hyperglycemia in Type 1 Diabetic Mice

Aleksunes, L. M., Reisman, S. A., Yeager, R. L., Goedken, M. J., Klaassen, C. D.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2010

Language:

english

File:

PDF, 3.18 MB

english, 2010

42

Differential regulation of intestinal efflux transporters by pregnancy in mice

Moscovitz, Jamie E., Yarmush, Gabriel, Herrera-Garcia, Guadalupe, Guo, Grace L., Aleksunes, Lauren M.

Journal:

Year:

2017

Language:

english

File:

PDF, 739 KB

english, 2017

43

Placental Drug Transport-on-a-Chip: A Microengineered In Vitro Model of Transporter-Mediated Drug Efflux in the Human Placental Barrier

Blundell, Cassidy, Yi, Yoon-Suk, Ma, Lin, Tess, Emily R., Farrell, Megan J., Georgescu, Andrei, Aleksunes, Lauren M., Huh, Dongeun

Journal:

Advanced Healthcare Materials

Year:

2017

Language:

english

File:

PDF, 2.19 MB

english, 2017

44

Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2

Lauren M. Aleksunes, Angela L. Slitt, Jonathan M. Maher, Lisa M. Augustine, Michael J. Goedken, Jefferson Y. Chan, Nathan J. Cherrington, Curtis D. Klaassen, José E. Manautou

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.24 MB

english, 2008

45

Placental BCRP/ ABCG2 transporter prevents fetal exposure to the estrogenic mycotoxin zearalenone

Szilagyi, John T, Gorczyca, Ludwik, Brinker, Anita, Buckley, Brian, Laskin, Jeffrey D, Aleksunes, Lauren M

Journal:

Toxicological Sciences

Year:

2018

Language:

english

File:

PDF, 1.62 MB

english, 2018

46

Brain region‐specific regulation of histone acetylation and efflux transporters in mice

You, Dahea, Shin, Hye Min, Mosaad, Fatimah, Richardson, Jason R., Aleksunes, Lauren M.

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2019

File:

PDF, 617 KB

2019

47

Pharmacogenomic Variants May Influence the Urinary Excretion of Novel Kidney Injury Biomarkers in Patients Receiving Cisplatin

Chang, Cara, Hu, Yichun, Hogan, Susan, Mercke, Nickie, Gomez, Madeleine, O’Bryant, Cindy, Bowles, Daniel, George, Blessy, Wen, Xia, Aleksunes, Lauren, Joy, Melanie

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

48

Coordinated Regulation of Hepatic Phase I and II Drug-Metabolizing Genes and Transporters using AhR-, CAR-, PXR-, PPAR -, and Nrf2-Null Mice

Aleksunes, L. M., Klaassen, C. D.

Journal:

Drug Metabolism and Disposition

Year:

2012

Language:

english

File:

PDF, 6.15 MB

english, 2012

49

Effects of Developmental Deltamethrin Exposure on White Adipose Tissue Gene Expression

Armstrong, Laura E., Driscoll, Maureen V., More, Vijay R., Donepudi, Ajay C., Xu, Jialin, Baker, Angela, Aleksunes, Lauren M., Richardson, Jason R., Slitt, Angela L.

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2013

Language:

english

File:

PDF, 122 KB

english, 2013

50

MDR1 Transporter Protects Against Paraquat-Induced Toxicity in Human and Mouse Proximal Tubule Cells

Wen, X., Gibson, C. J., Yang, I., Buckley, B., Goedken, M. J., Richardson, J. R., Aleksunes, L. M.

Journal:

Toxicological Sciences

Year:

2014

Language:

english

File:

PDF, 5.42 MB

english, 2014

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